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[2022-Vol.19-Issue 2]Synthesis and Antibacterial Properties of ZIF-8/Ag-Modified Titanium Alloy
Post: 2022-04-07 20:57  View:190

Journal of Bionic Engineering (2022) 19:507–515  https://doi.org/10.1007/s42235-021-00135-3

Synthesis and Antibacterial Properties of ZIF-8/Ag-Modifed Titanium Alloy 

Mingrui Li1  · Yongjie Wei1  · Bowen Ma1  · Yang Hu1  · Dongdong Li2  · Xiaoqiang Cui1 

1 Key Laboratory of Automobile Materials of MOE, Department of Materials Science and Engineering, Jilin University, Changchun 130022, China
2 State Key Laboratory for Materials Processing and Die and Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China

Abstract  The loosening of implant due to bacterial infection brings great difculties to the implantation of bionic titanium devices. In this study, the Zeolitic Imidazolate Framework 8 (ZIF-8) and silver ions were added to the surface of titanium alloy to obtain a uniform coating, which has nice biological activity and antibacterial property. The material structure characterizations, such as X-ray difraction (XRD), scanning electron microscope (SEM), X-ray photoelectron spectroscopy (XPS), proved that titanium is successfully modifed with ZIF-8 and silver ions. It has micro- and nano-level characteristics, rough porous morphology, and excellent apatite inducing ability. The water contact angle experiment shows that the addition of ZIF-8 greatly increases the hydrophilicity of material, which provides conditions for the attachment of osteoblasts. The polarization curve obtained from the electrochemical test proves that the addition of ZIF-8 coating improves the corrosion resistance of titanium. The release of silver ion has a strong growth inhibitory efect on E. coli, and exhibits excellent antibacterial properties. Therefore, the preparation of ZIF-8/Ag coatings on 3D printed titanium provides a new option for the development of orthopedic implants. 

Keywords  Zeolitic imidazolate framework-8 · Antibacterial · Osseointegration · Surface modifcation

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Preparing of ZIF-8 and ZIF8-Ag coating on Ti6Al4V sheet

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